A single amino acid change determines persistence of a chimeric Theiler's virus.

The DA strain of Theiler's virus persists in the central nervous system of mice and causes chronic inflammation and demyelination. On the other hand, the GDVII strain causes an acute encephalitis and does not persist in surviving animals. Series of recombinants between infectious cDNA clones of...

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Detalhes bibliográficos
Main Authors: Jarousse, N, Grant, R A, Hogle, J M, Zhang, L, Senkowski, A, Roos, R P, Michiels, T, Brahic, M, McAllister, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236827/
https://ncbi.nlm.nih.gov/pubmed/7512164
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