A single amino acid change determines persistence of a chimeric Theiler's virus.

The DA strain of Theiler's virus persists in the central nervous system of mice and causes chronic inflammation and demyelination. On the other hand, the GDVII strain causes an acute encephalitis and does not persist in surviving animals. Series of recombinants between infectious cDNA clones of the...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Jarousse, N, Grant, R A, Hogle, J M, Zhang, L, Senkowski, A, Roos, R P, Michiels, T, Brahic, M, McAllister, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7512164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3364-3368.1994
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