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Noncytopathic Sindbis virus RNA vectors for heterologous gene expression

Infection of vertebrate cells with alphaviruses normally leads to prodigious expression of virus-encoded genes and a dramatic inhibition of host protein synthesis. Recombinant Sindbis viruses and replicons have been useful as vectors for high level foreign gene expression, but the cytopathic effects...

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Bibliografske podrobnosti
Main Authors: Agapov, Eugene V., Frolov, Ilya, Lindenbach, Brett D., Prágai, Béla M., Schlesinger, Sondra, Rice, Charles M.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC23682/
https://ncbi.nlm.nih.gov/pubmed/9789028
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