Noncytopathic Sindbis virus RNA vectors for heterologous gene expression
Infection of vertebrate cells with alphaviruses normally leads to prodigious expression of virus-encoded genes and a dramatic inhibition of host protein synthesis. Recombinant Sindbis viruses and replicons have been useful as vectors for high level foreign gene expression, but the cytopathic effects...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23682/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789028/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.12989 |
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