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Selection of RNA Replicons Capable of Persistent Noncytopathic Replication in Mammalian Cells

The natural life cycle of alphaviruses, a group of plus-strand RNA viruses, involves transmission to vertebrate hosts via mosquitoes. Chronic infections are established in mosquitoes (and usually in mosquito cell cultures), but infection of susceptible vertebrate cells typically results in rapid shu...

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Detalhes bibliográficos
Main Authors: Frolov, Ilya, Agapov, Eugene, Hoffman, Thomas A., Prágai, Béla M., Lippa, Mara, Schlesinger, Sondra, Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104163/
https://ncbi.nlm.nih.gov/pubmed/10196280
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