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Generation of ρ(0) cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses
Eukaryotic cells devoid of mitochondrial DNA (ρ(0) cells) were originally generated under artificial growth conditions utilizing ethidium bromide. The chemical is known to intercalate preferentially with the mitochondrial double-stranded DNA thereby interfering with enzymes of the replication machin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367725/ https://ncbi.nlm.nih.gov/pubmed/18353857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn124 |
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