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Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease

The DNA structure-selective endonuclease Mus81-Mms4/Eme1 is a context-specific recombination factor that supports DNA replication, but is not essential for DSB repair in Saccharomyces cerevisiae. We overexpressed Mus81-Mms4 in S. cerevisiae, purified the heterodimer to apparent homogeneity, and perf...

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Bibliographic Details
Main Authors: Ehmsen, Kirk Tevebaugh, Heyer, Wolf-Dietrich
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367710/
https://ncbi.nlm.nih.gov/pubmed/18281703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1152
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