Homolog-scanning mutagenesis reveals poliovirus receptor residues important for virus binding and replication.

Poliovirus initiates infection of primate cells by binding to the poliovirus receptor, Pvr. Mouse cells do not bind poliovirus but express a Pvr homolog, Mph, that does not function as a poliovirus receptor. Previous work has shown that the first immunoglobulin-like domain of the Pvr protein contain...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Morrison, M E, He, Y J, Wien, M W, Hogle, J M, Racaniello, V R
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2578-2588.1994
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