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Homolog-scanning mutagenesis reveals poliovirus receptor residues important for virus binding and replication.

Poliovirus initiates infection of primate cells by binding to the poliovirus receptor, Pvr. Mouse cells do not bind poliovirus but express a Pvr homolog, Mph, that does not function as a poliovirus receptor. Previous work has shown that the first immunoglobulin-like domain of the Pvr protein contain...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Morrison, M E, He, Y J, Wien, M W, Hogle, J M, Racaniello, V R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2578-2588.1994
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