Specific AAV Serotypes Stably Transduce Primary Hippocampal and Cortical Cultures with High Efficiency and Low Toxicity

Most current methods of gene delivery for primary cultured hippocampal neurons are limited by toxicity, transient expression, the use of immature neurons, and/or low efficiency. We performed a direct comparison of seven serotypes of adeno-associated virus (AAV) vectors for genetic manipulation of pr...

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Main Authors: Royo, Nicolas C., Vandenberghe, Luk H., Ma, Jing-Yuan, Hauspurg, Alisse, Yu, LiYa, Maronski, Margaret, Johnston, Julie, Dichter, Marc A., Wilson, James M., Watson, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367141/
https://ncbi.nlm.nih.gov/pubmed/18054899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.11.015
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