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Roles of Amino Acids and Subunits in Determining the Inhibition of Nicotinic Acetylcholine Receptors by Competitive Antagonists

BACKGROUND: Binding sites for agonists and competitive antagonists (nondepolarizing neuromuscular blocking agents) are located at the α–δ and α–ε subunit interfaces of adult nicotinic acetylcholine receptors. Most information about the amino acids that participate in antagonist binding comes from bi...

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Bibliografiska uppgifter
Huvudupphovsmän: Dilger, James P., Vidal, Ana Maria, Liu, Man, Mettewie, Claire, Suzuki, Takahiro, Pham, Anh, Demazumder, Deeptankar
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367005/
https://ncbi.nlm.nih.gov/pubmed/17525594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.anes.0000267602.94516.7f
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