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Determinants of Competitive Antagonist Sensitivity on Neuronal Nicotinic Receptor β Subunits

We constructed a series of chimeric and mutant neuronal nicotinic acetylcholine receptor β subunits to map amino acid residues that determine sensitivity to competitive antagonists. The β2 and β4 subunits form pharmacologically distinct receptors when expressed in combination with the α3 subunit in...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Harvey, Scott C., Luetje, Charles W.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578601/
https://ncbi.nlm.nih.gov/pubmed/8656274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-12-03798.1996
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