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Free-energy landscape of a chameleon sequence in explicit water and its inherent α/β bifacial property
A sequence in yeast MATα2/MCM1/DNA complex that folds into α-helix or β-hairpin depending on the surroundings has been known as "chameleon" sequence. We obtained the free-energy landscape of this sequence by using a generalized-ensemble method, multicanonical molecular dynamics simulation,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366969/ https://ncbi.nlm.nih.gov/pubmed/14573865 |
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