Modulation of cyclin gene expression by adenovirus E1A in a cell line with E1A-dependent conditional proliferation.

To investigate how adenovirus E1A controls cell proliferation, we have fused E1A to the hormone-binding domain of the human estrogen receptor (ER) and introduced the E1A-ER chimeric gene together with an activated ras gene into primary rat embryo fibroblasts. Cell lines derived from this transfectio...

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Detalhes bibliográficos
Main Authors: Spitkovsky, D, Steiner, P, Lukas, J, Lees, E, Pagano, M, Schulze, A, Joswig, S, Picard, D, Tommasino, M, Eilers, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236696/
https://ncbi.nlm.nih.gov/pubmed/8139005
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