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Effect of Fgd1 on Cortactin in Arp2/3 Complex-Mediated Actin Assembly
Mutations in faciogenital dysplasia protein (Fgd1) result in the human disease faciogenital dysplasia (FGDY). Fgd1 contains a RhoGEF domain specific for Cdc42. Fgd1 also contains a Src homology (SH3) binding domain (SH3-BD) that binds directly to the SH3 domain of cortactin, which promotes actin ass...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366894/ https://ncbi.nlm.nih.gov/pubmed/14992579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi036173t |
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