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The Nup358-RanGAP Complex Is Required for Efficient Importin α/β-dependent Nuclear Import

In vertebrate cells, the nucleoporin Nup358/RanBP2 is a major component of the filaments that emanate from the nuclear pore complex into the cytoplasm. Nup358 forms a complex with SUMOylated RanGAP1, the GTPase activating protein for Ran. RanGAP1 plays a pivotal role in the establishment of a RanGTP...

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Detalhes bibliográficos
Main Authors: Hutten, Saskia, Flotho, Annette, Melchior, Frauke, Kehlenbach, Ralph H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366868/
https://ncbi.nlm.nih.gov/pubmed/18305100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1279
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