Importin 7 and Nup358 Promote Nuclear Import of the Protein Component of Human Telomerase

In actively dividing eukaryotic cells, chromosome ends (telomeres) are subject to progressive shortening, unless they are maintained by the action of telomerase, a dedicated enzyme that adds DNA sequence repeats to chromosomal 3′end. For its enzymatic function on telomeres, telomerase requires nucle...

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Bibliografiske detaljer
Main Authors: Frohnert, Cornelia, Hutten, Saskia, Wälde, Sarah, Nath, Annegret, Kehlenbach, Ralph H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930611/
https://ncbi.nlm.nih.gov/pubmed/24586428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088887
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