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Direct measurement of T-cell receptor repertoire diversity with AmpliCot

Many studies require the measurement of nucleic acid sequence diversity. Here we describe a method, called AmpliCot, that measures the sequence diversity of PCR products on the basis of DNA hybridization kinetics, thereby avoiding the time, expense and biases associated with cloning and sequencing....

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Bibliografski detalji
Glavni autori: Baum, Paul D, McCune, Joseph M
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366817/
https://ncbi.nlm.nih.gov/pubmed/17060913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/NMETH949
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