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Mucosal Adjuvant Activity of Flagellin in Aged Mice

We evaluated the ability of flagellin, a highly effective mucosal adjuvant in mice and non-human primates, to promote mucosal innate and adaptive immunity in aged mice. We found that intratracheal instillation of flagellin induced a stronger respiratory innate response in aged mice than in young mic...

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Main Authors: Bates, John T., Honko, Anna N., Graff, Aaron A., Kock, Nancy D., Mizel, Steven B.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366812/
https://ncbi.nlm.nih.gov/pubmed/18367233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.01.009
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