Engineered Expression of the TLR5 Ligand Flagellin Enhances Paramyxovirus Activation of Human Dendritic Cell Function

The paramyxovirus simian virus 5 (SV5) is a poor activator of human dendritic cell (DC) maturation pathways in vitro, and infected DC do not upregulate cell surface costimulatory proteins or secretion of immunomodulatory cytokines. We evaluated the hypothesis that activation of SV5-infected DC would...

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Détails bibliographiques
Auteurs principaux: Arimilli, Subhashini, Johnson, John B., Clark, Kimberly M., Graff, Aaron H., Alexander-Miller, Martha A., Mizel, Steven B., Parks, Griffith D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2008
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573257/
https://ncbi.nlm.nih.gov/pubmed/18787007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01288-08
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