Engineered Expression of the TLR5 Ligand Flagellin Enhances Paramyxovirus Activation of Human Dendritic Cell Function

The paramyxovirus simian virus 5 (SV5) is a poor activator of human dendritic cell (DC) maturation pathways in vitro, and infected DC do not upregulate cell surface costimulatory proteins or secretion of immunomodulatory cytokines. We evaluated the hypothesis that activation of SV5-infected DC would...

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Detalhes bibliográficos
Main Authors: Arimilli, Subhashini, Johnson, John B., Clark, Kimberly M., Graff, Aaron H., Alexander-Miller, Martha A., Mizel, Steven B., Parks, Griffith D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573257/
https://ncbi.nlm.nih.gov/pubmed/18787007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01288-08
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