Engineered Expression of the TLR5 Ligand Flagellin Enhances Paramyxovirus Activation of Human Dendritic Cell Function

The paramyxovirus simian virus 5 (SV5) is a poor activator of human dendritic cell (DC) maturation pathways in vitro, and infected DC do not upregulate cell surface costimulatory proteins or secretion of immunomodulatory cytokines. We evaluated the hypothesis that activation of SV5-infected DC would...

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Autores principales: Arimilli, Subhashini, Johnson, John B., Clark, Kimberly M., Graff, Aaron H., Alexander-Miller, Martha A., Mizel, Steven B., Parks, Griffith D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573257/
https://ncbi.nlm.nih.gov/pubmed/18787007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01288-08
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