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Engineered Expression of the TLR5 Ligand Flagellin Enhances Paramyxovirus Activation of Human Dendritic Cell Function

The paramyxovirus simian virus 5 (SV5) is a poor activator of human dendritic cell (DC) maturation pathways in vitro, and infected DC do not upregulate cell surface costimulatory proteins or secretion of immunomodulatory cytokines. We evaluated the hypothesis that activation of SV5-infected DC would...

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Main Authors: Arimilli, Subhashini, Johnson, John B., Clark, Kimberly M., Graff, Aaron H., Alexander-Miller, Martha A., Mizel, Steven B., Parks, Griffith D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573257/
https://ncbi.nlm.nih.gov/pubmed/18787007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01288-08
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