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Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene.

Major transcriptional control elements are located within the U3 region of the long terminal repeats (LTRs) of lentivirus and other retroviral genomes. The nef auxiliary gene of simian immunodeficiency virus (SIV) and human immunodeficiency virus overlaps about 70% of the 450- to 560-bp-long U3 regi...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kirchhoff, F, Kestler, H W, Desrosiers, R C
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236672/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.2031-2037.1994
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