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Antigenicity of the N8 influenza A virus neuraminidase: existence of an epitope at the subunit interface of the neuraminidase.

To locate antigenic epitopes on the N8 neuraminidase (NA), we generated a panel of 97 monoclonal antibodies (MAbs), 66 of which inhibited NA activity (NI antibodies). Three groups of NI MAbs were identified from their different reactivities with escape mutants. Group 1 antibodies recognized the pept...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Saito, T, Taylor, G, Laver, W G, Kawaoka, Y, Webster, R G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236640/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1790-1796.1994
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