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Antigenicity of the N8 influenza A virus neuraminidase: existence of an epitope at the subunit interface of the neuraminidase.

To locate antigenic epitopes on the N8 neuraminidase (NA), we generated a panel of 97 monoclonal antibodies (MAbs), 66 of which inhibited NA activity (NI antibodies). Three groups of NI MAbs were identified from their different reactivities with escape mutants. Group 1 antibodies recognized the pept...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Saito, T, Taylor, G, Laver, W G, Kawaoka, Y, Webster, R G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC236640/
https://ncbi.nlm.nih.gov/pubmed/7509002
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