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Trefoil Factor 3 Stimulates Human and Rodent Pancreatic Islet β-Cell Replication with Retention of Function
Both major forms of diabetes involve a decline in β-cell mass, mediated by autoimmune destruction of insulin-producing cells in type 1 diabetes and by increased rates of apoptosis secondary to metabolic stress in type 2 diabetes. Methods for controlled expansion of β-cell mass are currently not avai...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Endocrine Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366186/ https://ncbi.nlm.nih.gov/pubmed/18258687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0500 |
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