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Trefoil Factor 3 Stimulates Human and Rodent Pancreatic Islet β-Cell Replication with Retention of Function

Both major forms of diabetes involve a decline in β-cell mass, mediated by autoimmune destruction of insulin-producing cells in type 1 diabetes and by increased rates of apoptosis secondary to metabolic stress in type 2 diabetes. Methods for controlled expansion of β-cell mass are currently not avai...

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Detalhes bibliográficos
Main Authors: Fueger, Patrick T., Schisler, Jonathan C., Lu, Danhong, Babu, Daniella A., Mirmira, Raghavendra G., Newgard, Christopher B., Hohmeier, Hans E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366186/
https://ncbi.nlm.nih.gov/pubmed/18258687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0500
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