Estrogen Receptors α and β as Determinants of Gene Expression: Influence of Ligand, Dose, and Chromatin Binding

Estrogen receptors α and β (ERα and ERβ) mediate the actions of estrogens in a variety of normal and cancer target cells. Estrogens differ in their preference for these ERs, and many phytoestrogens bind preferentially to ERβ. To investigate how phytoestrogens such as genistein impact ER-regulated ge...

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Detalhes bibliográficos
Main Authors: Chang, Edmund C., Charn, Tze Howe, Park, Sung-Hee, Helferich, William G., Komm, Barry, Katzenellenbogen, John A., Katzenellenbogen, Benita S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366177/
https://ncbi.nlm.nih.gov/pubmed/18258689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0356
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