Genome-Wide Analysis of Estrogen Receptor α DNA Binding and Tethering Mechanisms Identifies Runx1 as a Novel Tethering Factor in Receptor-Mediated Transcriptional Activation

Nuclear receptor estrogen receptor alpha (ERα) controls the expression of hundreds of genes responsible for target cell phenotypic properties, but the relative importance of direct versus tethering mechanisms of DNA binding has not been established. In this first report, we examine the genome-wide c...

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Main Authors: Stender, Joshua D., Kim, Kyuri, Charn, Tze Howe, Komm, Barry, Chang, Ken C. N., Kraus, W. Lee, Benner, Christopher, Glass, Christopher K., Katzenellenbogen, Benita S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916448/
https://ncbi.nlm.nih.gov/pubmed/20547749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00118-10
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