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Critical Amino Acids in the Active Site of Meprin Metalloproteinases for Substrate and Peptide Bond Specificity

The protease domains of the evolutionarily-related α and ß subunits of meprin metalloproteases are approximately 55% identical at the amino acid level, however, their substrate and peptide bond specificities differ markedly. The meprin ß subunit favors acidic residues proximal to the scissile bond,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Villa, James P., Bertenshaw, Greg P., Bond, Judith S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366086/
https://ncbi.nlm.nih.gov/pubmed/12888571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M303718200
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