Cellular Uptake, DNA Binding and Apoptosis Induction of Cytotoxic Trans-[PtCl(2)(N,N-dimethylamine)(Isopropylamine)] in A2780cisR Ovarian Tumor Cells

Trans-[PtCl(2)(N,N-dimethylamine)(isopropylamine)] is a novel trans-platinum compound that shows cytotoxic activity in several cisplatin resistant cell lines. The aim of this paper was to analyse, by means of molecular cell biology techniques and total reflection X-ray fluorescence (TXRF), the cytot...

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Detalhes bibliográficos
Main Authors: Pérez, José M., Montero, Eva I., Quiroga, Adoración G., Fuertes, Miguel A, Alonso, Carlos, Navarro-Ranninger, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365251/
https://ncbi.nlm.nih.gov/pubmed/18475973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.2001.29
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