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Cytotoxic Action of Carboxyborane Heterocyclic Amine Adducts

The heterocyclic carboxyborane amines were found to be potent cytotoxic agents in the murine L1210 lymphoid leukemia and human HeLa suspended carcinoma cells. These agents were observed to inhibit HeLa DNA topoisomerase II activity ~ 200 μM and L1210 topoisomerase II activity ≥ 100 μM. These agents...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Miller, Merrill C., Sood, Anup, Spielvogel, Bernard F., Bastow, Ken, Hall, Iris H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365064/
https://ncbi.nlm.nih.gov/pubmed/18475792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1997.229
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