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Cytotoxic Action of Carboxyborane Heterocyclic Amine Adducts
The heterocyclic carboxyborane amines were found to be potent cytotoxic agents in the murine L1210 lymphoid leukemia and human HeLa suspended carcinoma cells. These agents were observed to inhibit HeLa DNA topoisomerase II activity ~ 200 μM and L1210 topoisomerase II activity ≥ 100 μM. These agents...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2365064/ https://ncbi.nlm.nih.gov/pubmed/18475792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1997.229 |
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