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Degradation of Anthracycline Antitumor Compounds Catalysed by Metal Ions
The influence of some metal ions on the degradation of anthracyclines was examined. One of the degradation products is the 7,8-dehydro-9,10-desacetyldoxorubicinone, D* (¥), usually formed by hydrolysis at slightly basic pH. D* is a lipophilic compound with no cytostatic properties. Its formation cou...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
1994
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364892/ https://ncbi.nlm.nih.gov/pubmed/18476230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1994.183 |
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