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Degradation of Anthracycline Antitumor Compounds Catalysed by Metal Ions

The influence of some metal ions on the degradation of anthracyclines was examined. One of the degradation products is the 7,8-dehydro-9,10-desacetyldoxorubicinone, D* (¥), usually formed by hydrolysis at slightly basic pH. D* is a lipophilic compound with no cytostatic properties. Its formation cou...

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Detalhes bibliográficos
Main Authors: Fiallo, Marina M. L., Haj, Hayet Tayeb-Bel, Garnier-Suillerot, Arlette
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364892/
https://ncbi.nlm.nih.gov/pubmed/18476230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1994.183
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