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Analysis of Multidrug Transporter in Living Cells. Inhibition of P-glycoprotein-mediated Efflux of Anthracyclines by Ionophores

One of the major obstacles of chemotherapy is that, after repeated treatments, cellular resistance to the drug appears. The problem is that the tumor cells become resistant not only to the drugs which have been used during the treatment but also to other drugs which are structurally and functionally...

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Detalhes bibliográficos
Main Authors: Borrel, Marie-Nicole, Pereira, Elene, Fiallo, Marina, Garnier-Suillerot, Arlette
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364894/
https://ncbi.nlm.nih.gov/pubmed/18476229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1994.175
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