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Mutations in a CCHC zinc-binding motif of the reovirus sigma 3 protein decrease its intracellular stability.

It has been demonstrated that the sigma 3 protein of reovirus harbors a zinc-binding domain in its amino-terminal portion. A putative zinc finger in the CCHH form is located in this domain and was considered to be a good candidate for the zinc-binding motif. We performed site-directed mutagenesis to...

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Autors principals: Mabrouk, T, Lemay, G
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC236476/
https://ncbi.nlm.nih.gov/pubmed/8035527
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