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Mutations in a CCHC zinc-binding motif of the reovirus sigma 3 protein decrease its intracellular stability.

It has been demonstrated that the sigma 3 protein of reovirus harbors a zinc-binding domain in its amino-terminal portion. A putative zinc finger in the CCHH form is located in this domain and was considered to be a good candidate for the zinc-binding motif. We performed site-directed mutagenesis to...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Mabrouk, T, Lemay, G
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035527/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.5287-5290.1994
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