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Binding of the 5′-untranslated region of coronavirus RNA to zinc finger CCHC-type and RNA-binding motif 1 enhances viral replication and transcription

Coronaviruses RNA synthesis occurs in the cytoplasm and is regulated by host cell proteins. In a screen based on a yeast three-hybrid system using the 5′-untranslated region (5′-UTR) of SARS coronavirus (SARS-CoV) RNA as bait against a human cDNA library derived from HeLa cells, we found a positive...

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Библиографические подробности
Главные авторы: Tan, Yong Wah, Hong, Wanjin, Liu, Ding Xiang
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
Предметы:
RNA
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367200/
https://ncbi.nlm.nih.gov/pubmed/22362731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks165
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