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Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL

TNF-related apoptosis-inducing ligand (TRAIL, also known as Apo-2L) is a promising novel anticancer agent that selectively induces apoptosis in tumour cells and the activity of which can be enhanced by combined treatment with chemo- or radiotherapy. For therapeutic purposes, the use of full-length T...

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Autori principali: Abou El Hassan, M A I, Mastenbroek, D C J, Gerritsen, W R, Giaccone, G, Kruyt, F A E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364740/
https://ncbi.nlm.nih.gov/pubmed/15173860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601910
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