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The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

A critical microtubule (MT) polarization event in cell migration is the Rho/mDia-dependent stabilization of a subset of MTs oriented toward the direction of migration. Although mDia nucleates actin filaments, it is unclear whether this or a separate activity of mDia underlies MT stabilization. We ge...

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Hlavní autoři: Bartolini, Francesca, Moseley, James B., Schmoranzer, Jan, Cassimeris, Lynne, Goode, Bruce L., Gundersen, Gregg G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364705/
https://ncbi.nlm.nih.gov/pubmed/18458159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709029
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