Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes

Telomeres are maintained by three DNA-binding proteins (telomeric repeat binding factor 1 [TRF1], TRF2, and protector of telomeres 1 [POT1]) and several associated factors. One factor, TRF1-interacting protein 2 (TIN2), binds TRF1 and TRF2 directly and POT1 indirectly. Along with two other proteins,...

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Hlavní autoři: Kim, Sahn-ho, Davalos, Albert R., Heo, Seok-Jin, Rodier, Francis, Zou, Ying, Beausejour, Christian, Kaminker, Patrick, Yannone, Steven M., Campisi, Judith
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364703/
https://ncbi.nlm.nih.gov/pubmed/18443218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710028
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