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Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
Telomeres are maintained by three DNA-binding proteins (telomeric repeat binding factor 1 [TRF1], TRF2, and protector of telomeres 1 [POT1]) and several associated factors. One factor, TRF1-interacting protein 2 (TIN2), binds TRF1 and TRF2 directly and POT1 indirectly. Along with two other proteins,...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364703/ https://ncbi.nlm.nih.gov/pubmed/18443218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710028 |
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