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Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

Human immunodeficiency virus type 1 (HIV-1) Nef is a myristylated protein with a relative molecular mass of 27 kDa, is localized to the cytoplasmic surfaces of cellular membranes, and has been reported to down-modulate CD4 in human T cells. To understand the mechanism of HIV-1 Nef-mediated down-modu...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Rhee, S S, Marsh, J W
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236459/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035515/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.5156-5163.1994
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