Human Immunodeficiency Virus Nef Induces Rapid Internalization of the T-Cell Coreceptor CD8αβ

Human immunodeficiency virus (HIV) Nef is a membrane-associated protein decreasing surface expression of CD4, CD28, and major histocompatibility complex class I on infected cells. We report that Nef strongly down-modulates surface expression of the β-chain of the CD8αβ receptor by accelerated endocy...

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Main Authors: Stove, Veronique, Van de Walle, Inge, Naessens, Evelien, Coene, Elisabeth, Stove, Christophe, Plum, Jean, Verhasselt, Bruno
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193625/
https://ncbi.nlm.nih.gov/pubmed/16103193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11422-11433.2005
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