Down-Modulation of CD8αβ Is a Fundamental Activity of Primate Lentiviral Nef Proteins

It is well established that the Nef proteins of human and simian immunodeficiency viruses (HIV and SIV) modulate major histocompatibility complex class I (MHC-I) cell surface expression to protect infected cells against lysis by cytotoxic T lymphocytes (CTLs). Recent data supported the observation t...

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Detalhes bibliográficos
Main Authors: Heigele, Anke, Schindler, Michael, Gnanadurai, Clement W., Leonard, Jolie A., Collins, Kathleen L., Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255914/
https://ncbi.nlm.nih.gov/pubmed/22013062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00717-11
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