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Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.

We have used baculovirus-expressed Rep68 that has been purified to homogeneity to reexamine the binding properties of the Rep protein. We find that Rep68 is capable of binding to a linear DNA sequence that is contained within a 25-bp sequence of the A stem of the adeno-associated virus (AAV) termina...

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Autors principals: McCarty, D M, Pereira, D J, Zolotukhin, I, Zhou, X, Ryan, J H, Muzyczka, N
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC236440/
https://ncbi.nlm.nih.gov/pubmed/8035498
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