Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.

We have used baculovirus-expressed Rep68 that has been purified to homogeneity to reexamine the binding properties of the Rep protein. We find that Rep68 is capable of binding to a linear DNA sequence that is contained within a 25-bp sequence of the A stem of the adeno-associated virus (AAV) termina...

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Vydáno v:	J Virol
Hlavní autoři:	McCarty, D M, Pereira, D J, Zolotukhin, I, Zhou, X, Ryan, J H, Muzyczka, N
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035498/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.4988-4997.1994
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