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Analysis of mutations in adeno-associated virus Rep protein in vivo and in vitro.

The adeno-associated virus (AAV) Rep protein is required for both viral DNA replication and transactivation of the AAV promoters. Here we report the effects of mutations in the rep gene on transcription and replication in vivo and terminal repeat binding and terminal resolution site (trs) endonuclea...

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Bibliografiske detaljer
Main Authors: McCarty, D M, Ni, T H, Muzyczka, N
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC241207/
https://ncbi.nlm.nih.gov/pubmed/1318396
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