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A phase I dose-escalating study of DaunoXome, liposomal daunorubicin, in metastatic breast cancer

The aims of this phase I study were to establish the maximum tolerated dose, safety profile and activity of liposomal daunorubicin, DaunoXome (NeXstar Pharmaceuticals), in the treatment of metastatic breast cancer. DaunoXome was administered intravenously over 2 h in 21 day cycles and doses were inc...

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Detalhes bibliográficos
Main Authors: O'Byrne, K J, Thomas, A L, Sharma, R A, DeCatris, M, Shields, F, Beare, S, Steward, W P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364277/
https://ncbi.nlm.nih.gov/pubmed/12085249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600344
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