A phase I study of intravenous liposomal daunorubicin (DaunoXome) in paediatric patients with relapsed or resistant solid tumours

Anthracyclines are widely used in paediatric oncology, but their use is limited by the risk of cumulative cardiac toxicity. Encapsulating anthracyclines in liposomes may reduce cardiac toxicity and possibly increase drug availability to tumours. A phase I study in paediatric patients was designed to...

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Autori principali: Lowis, S, Lewis, I, Elsworth, A, Weston, C, Doz, F, Vassal, G, Bellott, R, Robert, J, Pein, F, Ablett, S, Pinkerton, R, Frappaz, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360691/
https://ncbi.nlm.nih.gov/pubmed/16880787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603288
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