A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc(™)) in patients with locally advanced or metastatic cancer

PURPOSE: This study was conducted to investigate the safety and tolerability of increasing doses of liposomal curcumin in patients with metastatic cancer. Investigations of anti-tumor activity and of the pharmacokinetics of curcumin were secondary objectives. METHODS: In this phase I, single-center,...

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Publicat a:Cancer Chemother Pharmacol
Autors principals: Greil, Richard, Greil-Ressler, Sigrun, Weiss, Lukas, Schönlieb, Charlotte, Magnes, Teresa, Radl, Bianca, Bolger, Gordon T., Vcelar, Brigitta, Sordillo, Peter P.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132848/
https://ncbi.nlm.nih.gov/pubmed/30074076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3654-0
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