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Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes

We prepared small unilamellar liposomes derivatised with single chain antibody fragments specific for the ED-B domain of B-fibronectin. This extracellular matrix associated protein is expressed around newly forming blood vessels in the vicinity of many types of tumours. The single chain antibody fra...

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Bibliografische gegevens
Hoofdauteurs: Marty, C, Odermatt, B, Schott, H, Neri, D, Ballmer-Hofer, K, Klemenz, R, Schwendener, R A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364274/
https://ncbi.nlm.nih.gov/pubmed/12085265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600423
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